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Cutting is one of the most widely used machining technologies in the mechanical industry. Metal cutting is a complex technology process and innovation methodology is urgently for its innovation TRIZ is a technology innovation method of Soviet Union. Conflict tools of TRIZ are applied to the analysis process of machining technology of titanium alloy with standardize the description of conflict by 39 engineering parameters. With the computer-aided innovation system and corresponding inventive principles, the project of the process innovation of oxidation coating on biomedical titanium alloy is finished. The significance of TRIZ in promoting technology innovation is illustrated.