Aim:Acute preeclampsia is associated with significantly higher prevalence of asymptomatic global left ventricular (LV) abnormal function and myocardial injury than uneventful pregnancy. Hence, this study was undertaken to evaluate the LV changes in preeclamptic women and to compare with normotensive women.Materials and Methods:This study was conducted in the Department of Obstetrics and Gynaecology, M. S. Ramaiah Medical College and Teaching Hospital, Bengaluru. Two-hundred women were in each group: 200 patients with preeclampsia as cases and 200 normotensive patients as controls.Results:The mean LV end-systolic volume (LV ESV) in preeclamptic women was 33.45 ± 2.8, LV end-diastolic volume (LV EDV) was 106 ± 3.01, and LV systolic mass (LV Ms) was 87.1 ± 1.65 when compared to normotensive women LV ESV - 27 ± 0.74, (P < 0.0001) LV EDV - 106.2 ± 0.43, (P - 0.3528), and LV Ms - 84 ± 0.56 (P < 0.0001).Conclusion:This study emphasizes the importance of identifying this subset of preeclamptic patients with echo changes who are at higher risk of developing cardiovascular complications later in life by undergoing echocardiography.
Background:One of the leading gynecological malignancies is ovarian cancer. The current study was done to study the histopathological pattern and clinical presentation of ovarian cancer in a tertiary care centre. The objective of the study was to study the clinical presentation, histopathological types of ovarian cancer and the outcome of the management. Methods: A retrospective study of the patients treated at the M. S. Ramaiah Medical College and Teaching hospital, Bangalore from a total period of 5 years, from January 2009 -January 2014. The epidemiological data and histopathological analysis of the ovarian cancer was done. Results: In the present study, a total of 106 ovarian cancer cases were included. Majority of the patients were in the age group 40-49 years (32%). Histopathological examination of the specimens revealed that serous adenocarcinoma was the commonest (42.4%) and the least common being yolk sac tumour (0.9%). Majority (n=49, 46.2%) of the patients presented in stage III. The chief complaint was abdominal pain (n=74,69.8%) followed by abdominal distension (n=55,51.8%). Conclusions: Majority of the patients who presented to us were in the perimenopausal age group at least 2 decades earlier to the western population and many of the patients presented with abdominal pain rather than abdominal distension. These observations warrant us to screen women at an earlier age and also think of this lethal malignancy in women who present with pain and other vague symptoms.
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