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Introduction: Danti, Baliospermum solanifolium (Burm.) Suresh [Syn. Baliospermum montanum (Willd.) Muell. Arg], of family Euphorbiaceae is an important herbal drug in the Ayurveda pharmacopoeia of India. In Ayurveda, Samskara (processing) has been shown to increase the efficacy of various drugs. Shodhana (purificatory measures/processing) is one of the steps involved in Samskara. The Charaka samhita describes the Shodhana (processing) of Danti by applying the fruit powder of Pippali (Piper longum L.) along with honey, wrapping it with Kusha (Desmostachya bippinnata Stapf.), and then fomenting it. The root thus obtained is dried under sunrays and then stored for further use. The exact pharmacognostical changes that transpire through Samskara (classical processing technique) remain to be explored scientifically. Hence, an attempt has been made to evaluate the pharmacognostical changes in Danti root, including its powder microscopy.