This study aimed to investigate the key factors of sustainability of hotel social responsibility from the effectiveness of the hotel intern training system. Using a mixed research method, a sample was first selected by purposive sampling, and 280 questionnaires were obtained by snowballing from September 2019 to February 2020. Using Statistical package for social sciences (SPSS, AMOS) IBM 22.0 software, the reliability of the questionnaires was confirmed by the CFA method, examined by Pearson Correlation Analysis, and then the opinions of hoteliers, experts, and senior employees on the questionnaire results were obtained by interview method and finally, the data were compiled and analyzed by multivariate verification. The study found that: Chinese hoteliers are unable to stabilize their employees' motivation and fulfill their internal social responsibility due to insufficient human resource training system, welfare benefits, job rotation mechanism, and poorly defined reward and punishment system. In order to stabilize the implementation of perfect internal corporate responsibilities for entrepreneurs, it is necessary to strengthen corporate culture promotion, improve the existing promotion system, increase employee benefits, and adjust the working environment and facilities. In this way, even in a harsh working environment, it can still increase employees' recognition of the company, improve work performance, and increase employees' willingness to stay.