IgG4-RD is a systemic inflammatory and sclerosing disease. Parotid and lacrimal involvement (formerly called Mikulicz's disease), lymphadenopathy and pancreatitis are the most common manifestations. Patients with IgG4-RD showed favourable responses to treatment with glucocorticoids and immunosuppressive agents.
A new kind of composite zeolite catalyst containing multi-functional reactive-sites located in different nanopores with individual shape-selectivity was successfully applied to two complex one-pot (including both sequential and parallel) reactions. Every kind of reactant molecule was exactly catalyzed only for its desired reaction, thus the reactive pathways were effectively controlled.
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