Objective:The main objective of this study was to evaluate the knowledge, attitudes and practices (KAP) of health sciences students regarding epilepsy at the end of curriculum in Benin. Methods: We conducted a cross-sectional survey among medical, pharmacy, nursing and midwife students in their last-year of health sciences training in University of Abomey-Calavi in Benin. Students completed a self-administered questionnaire, containing items addressing demographics, epilepsy treatment, diagnosis, clinical practice, and social tolerance regarding person with epilepsy. Results: The response rate to our survey was 87.7% (n=164). The sample consisted of 64 medical students, 22 pharmacy students, 43 nursing students and 35 midwife students. They were divided into 95 female subjects and 69 male; sex ratio was 0.7. The mean age of participants was 23.6±1.8 years. The mean scores for epilepsy knowledge, practices and attitudes were respectively 7.6±1.7 out of a maximum score of 11, 3.9±1.8 out of 8 and 9.6±0.8 out of 10. The KAP overall score was 21.1±3.4 out of a maximum score of 29.0. The variables associated with the overall KAP score were training school, gender, having heard