The activity of these compounds against E.typhosa is considerably below that already reported for cetyltriethylammonium bromide and cetyltri-M-butylammonium bromide. Summary N -Carbamylmethyl, N-carbethoxymethyl and Nß-acetoxyethyl derivatives of several quaternary ammonium compounds containing one Ncetyl or N-lauryl group and three low molecular weight N-alkyl radicals were prepared. The germicidal activity of these compounds was studied, and in some, cases the effect on the activity of different anions was tested.In the N-lauryl group of compounds the germicidal activity was improved by the substitution of a carbethoxymethyl or /3-acetoxyethyl group for an original N-methyl radical. In the N-cetyl group the reverse was true. The halide salts and the nitrate all gave about the same activity. Organic anions usually lowered the activity of the compound. Cincinnati, Ohio

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