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The aim of this article is to present the main capabilities of an evolution code system, DARWIN, developed at CEA (France). It is devoted to radioactivity studies in various application fields such as nuclear fuel cycle, dismantling, thermonuclear fusion, accelerator driven system, medecine etc. All types of nuclides are dealt with: actinides, fission products, activation products, spallation products. Physical quantities calculated by the code are isotope concentration, isotope mass, activity, radiotoxicity, gamma spectra, beta spectra, alpha spectra, neutron production by spontaneous fission and (o:,n) reaction, residual heating, for any cooling times until geological times. Both analytical and numerical schemes are developed in the PEPIN2 depletion module of DARWIN to solve the generalized coupled differential depletion equations. The depletion module PEPIN2 is automatically linked to international evaluations (JEF2, ENDF /B6, EAF97 ...) both for decay data and cross-sections, and to some transport codes such as TRIPOLI, APOLL02 and ERANOS. These transport codes provide neutronic data as self-shielded cross-sections and neutron fluxes. DARWIN includes a generator of radioisotope chain built automatically from decay modes and nuclear reaction types specified in the evaluation libraries. A "search engine" allows to determine all formation ways of a considered isotope. Several examples are given for illustrating capabilities of DARWIN in different field applications. Some comparisons with other codes such as ORIGEN, FIS PIN and FISP ACT are also presented.

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