A straightforward three-component transformation for the preparation of functionalized benzosultams under TM-free and mild reaction conditions was described, in which easy-to-handle Na2S2O5, available bromodifluoroalkyl reagent, and N-(2-haloaryl) cyanamide were employed. Na2S2O5 was essential to the generation of difluoroalkyl radical, SO2 fixation, and cyclization, which enabled efficient construction of target products in a sustainable manner. A broad substrate scope and modular feature made this protocol attractive for exploring the chemical space of the construction of cyclic sulfonamides.

An electrochemical three-component transformation between N-cyanamide alkene, Na2S2O5 and sulfonyl hydrazide was described, in which various sulfonylated fused sultams were prepared in a sustainable and modular fashion. In this process,...

Correction for ‘Electrochemical tandem cyclization to access sulfonylated fused sultams via SO2 insertion with sodium metabisulfite’ by Yun-Hai Sun et al., Org. Chem. Front., 2023, 10, 705–711, https://doi.org/10.1039/D2QO01821G.

An efficient approach to construct α-amino cyclopentanones bearing consecutive quaternary and ternary carbon centers is desribed through a α‑iminol rearrangement enabled by Pd-catalyzed addition of arylboronic acids to nitriles. Variou...

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