The luminance and chromaticity measuring instruments of spectral radiation luminance meter have been widely used in the measurement field of flat panel display by virtue of a series of measurement advantages. In this paper, according to the unique metrological requirements of the flat panel display industry, the technical advantages of relevant measurement standards at home and abroad are analyzed, and the luminance chromaticity calibration device of spectral radiation luminance meter is developed according to the principle of integrating sphere luminance source and spectral color measurement. The metrological performance and characteristics of the calibration device are studied, and the measurement results of the device are verified. The results show that the calibration device meets the technical requirements as a measurement standard and can be used to calibrate the luminance and chromaticity parameters of the spectral radiation luminance meter.