This article described how further extensive variation of the substituents on the purine scaffold of adenosine triphosphate (ATP), and the human anti‐platelet aggregation activities were modified in order to find exploitation of the structure–activity relationships (SAR). A series of novel designed 6‐alkylamino‐2‐alkylthio‐9‐hydroxyalkyl(carbalkoxy) purine derivatives were synthesized via a modification procedure, and the human anti‐platelet aggregation activities were evaluated. The SAR of these compounds were analyzed in detail, and the results of the structural requirements of the substituents to improve potency may provide a basis for the development of potent P2Y12 antagonists.

This paper determined the total absorbance of phosphorus molybdenum blue and arsenic molybdenum blue by using the additive property of their absorbance values. By eliminating the interference of arsenic by reduction masking with composite reducing agent Na2SO3-Na2S2O3-KBr, the absorbance of phosphorus could be obtained. Thus, the content of phosphorus and arsenic could be calculated, respectively. The results show that the work curves of this method for phosphorus and arsenic are consistent with Beer’s law when the content of phosphorus and arsenic is 0-0.60ug/mL and 0-2.00ug/mL, respectively. The standard addition recovery rate of phosphorus and arsenic is 98.80%-101.04% and 99.00%-101.50%, respectively. The relative standard deviation of phosphorus and arsenic is less than 4.0% with good accuracy and precision. This method is simple and fast to determine phosphorus and arsenic in molybdenum concentrate, and the results are accurate and reliable.

Traditional measurement and modern SEM-based mineral liberation analysis (MLA) system were employed to obtain the process mineralogy characteristic of Jinshan gold ore which had high Au (6.20g/t) and low sulfide (0.25%). XBSE, XBSE_STD and SPL_Lt MLA modes are used in this case, which make the results timely, reliable and quantitative. The gold behaves irregular granular native gold or silver-bearing native gold of which the Au content ranging from 93%to 100%. Gold mainly occurred as liberated or in gold-carrying gangue minerals, such as quartz and biotite,rarely in pyrite in the form of fissure gold, inter-crystalline gold or inclusion gold . The particle size of the Gold minerals range from 0.001mm to 0.010mm , which is too fine to recover from beneficiating method. Combined process should be adopted.

This document develops a new spectrophotometric method for the determination of palladium with 4-(5-bromo-2-pyridyl)-azo-1,3-diaminobenzene, in a medium of 1.80mol/L sulfuric acid, at the maximum wavelength of 566nm. Absorption spectra of reagent and complex, effect of acidity, composition of complex and heating time for color reaction are discussed. More than 30 kinds of interfering ions are determined. The interference of Pb2+, Ag+ and Cr6+ are eliminated effectively by the proposed method. Beers law is obeyed in the concentration ranges of 0-1.0mg/L for palladium, the molar absorption coefficient is 6.44×104Lmol-1cm-1. The method is applied to the determination of palladium in general ores and palladium catalysts.

Arsenic, antimony and bismuth in gold ores were simultaneously determined by inductively coupled plasma optical emission spectrometry (ICP-OES) with spectral lines of 188.980, 206.834 and 223.061nm as analytical line respectively, under preset instrumental parameters. The linear range of the method for arsenic, antimony and bismuth was 0~80ug/mL and the correlation coefficient was greater than 0.99995. The detection limit for arsenic, antimony and bismuth was 2.87, 1.63 and 0.84ug/g respectively. The results of this method are consistent with the national standard method, and the relative error is less than 1.5%. The relative standard deviation (RSD) of this method is better than 5.0% (n=11) with good accuracy and precision. ICP-OES can be used for simultaneous determination of multiple elements and is suitable to the analysis of large quantities of samples.