This study investigated the expression of inflammatory factors in tumour tissues, monocytes and blood of non-small cell lung cancer (NSCLC) patients taking tetrandrine (Tet) during low-dose radiotherapy. Sixty NSCLC patients underwent surgical resection of lung cancer after low-dose radiotherapy. Thirty patients did not take Tet (control group) and the other thirty patients took Tet during radiotherapy (experimental group). Lung cancer tissues were collected from patients, and tumour-adjacent tissues were collected as controls. Peripheral blood was collected on the morning of radiotherapy for mononuclear cell separation. Quantitative real-time polymerase chain reaction was used to determine mRNA expression, and Western blotting was used to measure protein expression. Enzyme-linked immunosorbent assay was used to determine the inflammatory factor contents in liquid samples. Cell proliferation was determined via MTT assay at 24, 48 and 72 h after transfection in A549 cells. Tet reduced COX-2 mRNA in serum and blood monocytes and decreased COX-2 protein expression in monocytes from patients with radiotherapy. It decreased the release of inflammatory factors to blood after radiotherapy. Combined treatment with low-dose radiotherapy and Tet tablets reduced the expression of Ki-67 protein in tumour tissues, and decreased the release of inflammatory factors from NSCLC tissues after radiotherapy. Combined treatment with low-dose radiotherapy and Tet tablets reduced the proliferation of cancer cells possibly through reducing inflammatory factors released by tumour tissues. The study demonstrates that Tet administration during low-dose radiotherapy reduces the release of inflammatory factors by NSCLC tissues, and decreases tumour proliferation. Tet plays an auxiliary role in NSCLC radiotherapy.
Abstract-In this paper, chooses service failure and recovery of online shopping as the study's objective, analyses the effect of two different regulatory focus (promotion focus and prevention focus) and service recovery strategy on satisfaction. The results find that: the regulatory fit which arises from regulatory focus and service recovery strategy has significantly influence on perception fairness; perception fairness has significantly influence on satisfaction.
Based on Fisher & Rook's studies in 1995, this research establishes a model, choosing reference group's number (one person or multi-people) and reference group's proposal (encouragement, discouragement or neutrality) as independent variables, and analyses the effect of those independent variables on impulse buying through the normative evaluation. This research makes use of scenario planning to collect data, carries out the empirical study on the survey of 286 undergraduates and utilizes SPSS13.0 to analyze the collected data. The findings test and verify that normative evaluation has moderating effect between impulse buying intention and impulse buying behavior, and find that reference group's number and reference group's proposal can affect significantly normative evaluation and affect impulse buying through the mediating effect of normative evaluation.
Based on the panel data of 30 provinces in China from 2006 to 2019, this paper measures the coupling coordination degree of financial inclusion and agricultural green total factor productivity (AGTFP), and uses Dagum Gini coefficient and spatial feature analysis method to study the regional difference and spatial agglomeration state of coupling coordination degree. On this basis, it further discusses the impact of the improvement of the coupling co scheduling of financial inclusion and AGTFP on the urban-rural income gap. The results show that the overall level of financial inclusion and AGTFP is low, but both show a slow upward trend, and the degree of coupling and coordination between the two continues to improve, which has developed from the very low coordination stage to the primary coordination stage. The two show the characteristics of alternating changes of the relative lag of AGTFP and the relative lag of financial inclusion. At present, the main performance is the relative lag of financial inclusion. There are great regional differences in the coupling coordination degree of financial inclusion and AGTFP, but this regional difference is gradually narrowing; And its spatial pattern presents the characteristics of global positive autocorrelation and local spatial pattern evolution. Further discussion found that the improvement of the coupling and co scheduling of financial inclusion and AGTFP is conducive to narrowing the income gap between urban and rural areas. Therefore, in order to realize the sustainable development of agriculture, it is suggested to coordinate the relationship between financial inclusion and AGTFP.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.