A metal-free method for the regioselective synthesis of 2-thiolated quinolines from quinoline N-oxides in water at room tempera-ture is developed. The reaction is conducted by using benzenethiols as thiolation reagents...

A Pd-catalyzed annulation between 1-(2-iodophenyl)-1H-indoles and sodium difluorochloroacetate has been developed to synthesize 10H-indolo[1,2-a]indol-10-one derivatives via C-H bond activation and difluorocarbene transfer. Our route enables facile access to targeted products...

Owing to various chemical structures and different basicity of amines, a fluorescent probe that could distinguish aromatic and aliphatic amines is highly desirable for practical applications. Herein, an olefin-based, fluorescent COF (COFÀ PyÀ AN) with unique π-electron deficient groups was synthesized, which was a functionalized platform to realize sensing of π electron-rich aromatic amines. COFÀ PyÀ AN displayed fluorescence quenching in the presence of aromatic amines like aniline, with excellent selectivity against a variety of aromatic molecules, and the detection limit of COFÀ PyÀ AN toward aniline was as low as 1.29 μM. More importantly, COFÀ PyÀ AN could realize discriminating between aromatic and aliphatic amines. Furthermore, density functional theory calculations showed that the photoinduced electron transfer mechanism contributes to fluorescence sensing. This is the first example of olefin-based fluorescent COF materials for selective sensing of aromatic amines.