Solution-processed dye-sensitized ZnO phototransistors with extremely high photoresponsivity J. Appl. Phys. 112, 074507 (2012) Direct electrostatic toner marking with poly(3,4-ethylenedioxythiophene)polystyrenesulfonate bilayer devices J. Appl. Phys. 112, 074506 (2012) Modeling the effect of top gate voltage on the threshold of a double gate organic field effect transistor J. Appl. Phys. 112, 073704 (2012) Electron transporting water-gated thin film transistorsWe studied systematically the influence of in situ postannealing treatment of ultrahigh vacuum grown polycrystalline pentacene thin film transistor. The gradual grain growth with the elimination of defects and misoriented crystallites is confirmed in x-ray diffraction ͑XRD͒ data and the atomic force microscopy image as the annealing temperature increases. The XRD data reveal that the pentacene molecules are packed parallel to each other in an upright position with a tilting angle of 15.5°. The postannealing results in the enhanced field effect mobility of pentacene organic thin film transistors increases from 0.19Ϯ0.04 to 0.49Ϯ0.05 cm 2 /V s after annealing at 90°C. We suggest that the abnormally small on/off current ratio (ϳ10 3 ) due to the large leakage current is attributed to the conduction via impurity levels originated from the structural isomers of pentacene.
Pain is a distressing symptom of Parkinson disease (PD). We aim to determine whether the genetic variants of chronic pain-related genes contribute to pain in PD patients. We included 418 PD patients and evaluated pain severity on King’s PD pain scale. We genotyped rs6267, rs6269, rs4633, rs4818 and rs4680 of COMT, rs6746030 of SCN9A, and rs1799971 of OPRM1. In total, 193 participants (46.2%) experienced pain. Compared to pain-free PD patients, PD patients with pain had an earlier age of onset, longer disease duration, and higher depression and motor severity (P < 0.01). The frequencies of COMT rs4680 “A” allele were higher in PD patients with pain than those without pain (46.1% vs. 31.1%, P < 0.01). Pain severity was significantly associated with disease duration (P = 0.02), and COMT rs6267 T allele (P < 0.01). We stratified PD by status of depression and the association between COMT rs6267 “GT” genotype and pain severity remained significant (P < 0.01). Furthermore, pain severity was significantly higher in participants having COMT rs4680 “GG” and “GA” genpotypes than those having “AA” genotype (P = 0.04). We concluded that depression and COMT rs4680 “GG” and “GA” genotypes and COMT rs6267 “GT” genotype contribute to pain in PD patients.
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