Endocrine mucin-producing sweat gland carcinoma (EMPSGC) is a rare, low-grade skin adnexal neoplasm. It usually affects elderly patients, is more frequently observed in women, and has a predilection for the periorbital skin. It shares the same histological and immunohistochemical characteristics as solid papillary carcinoma (SPC) of the breast. 1 Local recurrences are common in EMPSGC, but metastases have not been reported until recently; 2-4 to date, only three cases have been reported, all of which involved ipsilateral parotid glands. Fine-needle aspiration cytology in these cases is difficult and is not usually performed. Herein, we report a case of eyelid EMPSGC metastatic to the contralateral eyelid and multiple salivary glands 8 years after the primary diagnosis.
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