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Lower LVEF, larger scar and/or more dyssynchrony assessed by MPS were related to the development of ventricular arrhythmia for patients with CRT, and further defibrillator implantation may be considered for these patients.

as decrease ≥10-20 ms in iQRSd after CRT) on ventricular arrhythmia are controversial. 2 In contrast, MRR is associated with significantly improved clinical outcomes. 3 The anti-arrhythmic effect of only MRR (only mechanical reverse remodeling) in patients with moderate-severe HF, however, is still controversial. 4, 5 We recently found that both ERR and MRR (ERR+MRR) after CRT had significantly more protective effects on ventricular arrhythmia than MRR only. 6-8 It is therefore clinically important to predict C ardiac resynchronization therapy (CRT) is the standard treatment for heart failure (HF) with baseline QRS morphology matching complete left bundle branch block (CLBBB) with prolonged intrinsic QRS duration (iQRSd). Background: The development of both electrical reverse remodeling and mechanical reverse remodeling (ERR+MRR) after cardiac resynchronization therapy (CRT) implantation could reduce the incidence of lethal arrhythmia, hence the prediction of ERR+MRR is clinically important.