Brinzolamide and timolol added to latanoprost have similar ocular hypotensive effects and safety in primary open-angle glaucoma, normal-tension glaucoma, or ocular hypertension.

A 50-year-old highly myopic Asian man had loss of vision in the left eye for 4 months. Visual acuity was 20/30 in the right eye and 20/40 in the left eye. Funduscopy disclosed a tilted disk, a large oval depression located in the region of the myopic conus ( Fig. 1), and a contiguous, transparent elevation of the macula in the left eye. No myopic staphyloma was noted. StratusOCT (Carl Zeiss Meditec, Dublin, CA) scans (Figs. 2 and 3) showed interruption of the hyperreflective band corresponding to the scleral tissue in the central region of the oval depression, along with signs of two distinct communications between the deeper spaces at the base of the anomaly and the neurosensory retina. One of the communica-The authors have no proprietary interest in the development or marketing of the device (or any competing device) mentioned in this report. Reprint requests: Fabio B. Aggio, MD, Alameda Jaú, 150 ap 21 B., Fig. 2. A, Ultrasonographic examination of the right eye (at initial presentation) showing a choroidal lesion surrounded by subretinal fluid. B, Marked increase in the size of the lesion depicted in A 2 months later.