All phase A subtypes were accompanied with increased heart rate variability, and the largest heart rate variability was seen in subtype A3, while a tendency for less heart rate variability was seen in subtype A1.

A case of syphilitic lymphadenitis of the neck, without syphilis of other regions, is presented. The patient was a 41-year-old man. A medical examination revealed a 35•~35 mm mass and swelling of several lymph

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Low-grade myofibroblastic sarcoma is an uncommon neoplasm of atypical myofibroblasts with fibromatosis-like features. The lesion has only been characterized in the last two decades, and the concept of neoplastic myofibroblasts remains controversial. We encountered a patient with low-grade myofibroblastic sarcoma of the maxilla. A 70-year-old woman was referred to our hospital because of swelling of the anterior maxilla. She had undergone repeated surgical procedures of the lesion at other hospitals. The tumor invaded the hard palate, nasal cavity, bilateral maxillary sinus, and cheek skin. The biopsy specimen showed a low-grade myofibroblastic sarcoma, and she underwent wide resection of the lesion and reconstructive surgery using a free forearm flap. Histologic examination revealed diffuse, fascicular proliferation of spindle cells with focal cellular atypia. The tumor cells showed positive reactions for α-SMA and vimentin, which indicated differentiation to myofibroblasts, and the lesion was diagnosed as a low-grade myofibroblastic sarcoma. The patient is free from tumor 13 months after surgery.

We have reported that most malignant melanomas of the oral mucosa are clinically and histologically identical to acral lentiginous melanoma (ALM) of the skin . There have been many studies of precusors of cutaneous melanoma, but few have mentioned oral melanoma.We describe our experience with a case of precancerous melanosis occurring in the hard palate . A 68-yearold woman was referred to our hospital because of a pigmented lesion of the palate, which her dentist had noticed accidentally. Clinical examinations revealed brownish-black plaque in the center of the lesion and adjacent light brown pigmented macules with no apparent borderline. She underwent surgical resection of the lesion via an intraoral approach for a diagnosis of a benign or premalignant melanocytic lesion . Histological examination revealed lentiginous or pagetoid proliferation of atypical melanocytes in the epithelial layer in the plaque lesion, with proliferation of dendritic melanocytes or simple hyperpigmentation in the macular lesion. These findings were identical to those of the radial growth phase of acral lentiginous melanoma of the oral cavity, which we reported previously. A diagnosis of a precursor lesion of ALM was made. She is free from disease 12 months after operation.