BACKGROUND Fibroadenomas are one of the most common benign tumours of the breast in the adolescent female population. Fibroadenomas can range from asymptomatic masses to painful and rapidly growing tumours that can cause significant aesthetic distortions of the breast. The aim of the study is to evaluate the outcome of centchroman use in the treatment of fibroadenoma of breast. MATERIALS AND METHODS The patients admitted in Dept. Of General Surgery, MKCG Medical College & Hospital with provisional diagnosis of fibroadenoma of breast from July 2015-June 2017, were included in the study. RESULTS 60 patients were included in the study, 40 patients had fibroadenoma of size more than 2cms and 20 patients had fibroadenoma of size less than 2cms. 40 (66.6%) patients had complete response with treatment and 20 (33.3%) patients not responded to treatment CONCLUSION Centchroman when given to patients of fibroadenoma of size less than 2cms has a good response. When the size of fibroadenoma is more than 2 cms, there is a mixed response. So further large scale study has to be done to evaluate its effectiveness.

BACKGROUNDDiabetic foot ulcer is a devastating complication of diabetes mellitus. The life time risk of developing an ulcer is estimated to be 15%. In a developing country like India, it is important to decrease the morbidity of such patients who if otherwise unchecked will lead on to amputation of the affected extremity and thereby increasing the disability status of the patient and thereby decreasing the overall health status of the country. This study compares the efficacy of Platelet Rich Plasma (PRP) dressing over conventional saline/povidone iodine dressing of diabetic ulcers and elicits a faster rate of ulcer healing with PRP dressing. The aim of this study was to compare the efficacy of autologous platelet rich plasma (PRP) over moist sterile saline povidone iodine dressing in diabetic foot ulcers-a randomized controlled study. MATERIALS AND METHODS60 diabetic patients with foot ulcers from the department of general surgery, were prospectively studied. Detailed clinical history, evaluation of ulcer and presence of wound infection were assessed for all the patients.