Synthesis of methoxy-substituted pyridinium-type ionic liquids from a nontoxic and easy method is described. Catalytic behaviors of synthesized ionic liquids were investigated with various concentrations for the Mannich reaction. We have observed that methoxy-and dimethoxy-substituted pyridinium bromides showed better catalytic behavior than other ionic liquids.

The synthesis of flexible dimeric pyridinium ionic liquids by both conventional and solid-supported approaches are described. We have optimized the Biginelli reaction with various concentrations of our synthesized ionic liquids with various counter ions. Among these, bromide-containing ionic liquids showed best catalytic activity.

Synthesis of 2‐hydroxy pyridinium type of ionic liquids is obtained via conventional as well as silica‐supported approaches. We found that solid‐supported reaction under muffle furnace condition has reduced the reaction nearly 20 times shorter than the conventional method. We have studied the catalytic activities of our synthesized pyridinium salts for one‐pot preparation of substituted quinolone derivatives and radical bromination of toluidine with optimized reaction conditions.

in Wiley Online Library (wileyonlinelibrary.com).The synthesis of pyridinium salts by both conventional/silica-supported muffle furnace and microwave approaches is described. We have optimized the Erlenmeyer synthesis of azalactone with various concentrations of our synthesized pyridinium salts. Among these, bromide-containing pyridinium salts showed excellent catalytic activity than the others.

We have prepared substituted flexible dimeric pyridinium bromide using conventional and greener approach. Solvent‐free solid phase (greener) approach is superior than the conventional owing to nontoxic, easy workup procedure, and 20 times lesser reaction time. Toxic organic solvents and column chromatography are avoided. Aldol condensation reaction is studied with various substituted aromatic aldehyde and compared with available recent literatures. Synthesized substituted flexible dimeric pyridinium salts acted as potential catalysts because of their better performance even in low concentration, recyclability, and activation of two molecules of aldehydes at the same time for aldol condensation reaction.