Background : Asthma is a common respiratory condition that affects an estimated 358 million people worldwide. Neutrophilic asthma is an asthma inflammatory phenotype associated with exacerbation,airflow limitation,and steroid resistance. Objective : The aim of the study was to observe the severity of Bronchial asthma in patients with Sputum Neutrophilia .Methods:This is a prospective cross sectional study by Department of Pulmonary Medicine including 50 patients with Acute Exacerbation of Bronchial Asthma as determined by ACQ. Results: Patients with sputum neutrophilia were seen to have higher ACQ scores,poor bronchodilator reversibility ,low expiratory volumes and poor response to inhaled corticosteroids with a higher risk of exacerbation.The correlation between sputum Neutrophilia and Bronchodilator reversibility using spirometry is statistically significant(p value = 0.0001) with a greater incidence of hospitalization for asthma.Conclusion:Neutrophilic asthma is associated with less atopy and these patients have lower levels of exhaled nitric oxide (FeNO), greater incidence of hospitalization for asthma and higher incidence of steroid resistance.Sputum neutrophilia has a positive correlation with smoking and is more often seen in older males

Introduction: Acute hypoxia is an important prognostic indicator in Chronic obstructive pulmonary disease (COPD) as a biomarker. RDW can aid in identification of persistent Hypoxia. Objective: To investigate the association of red cell Distribution Width (RDW) values in COPD exacerbation patients. Methods: This is a prospective cross-sectional study of 50 patients with COPD evaluated between September 2021 to December 2021.Hemogram,demographics,Spirometry and 2D echo data collected.Results: Mean age of the patients was 56 ± 10 years.Correlation between RDW with hypoxia, 6MWT,Pulmonary hypertension,CAT was found to be significant (p = 0.001 respectively) Patients with poor expiratory volumes (FEV1) were found to have higher CAT scores. Most patients in the study cohort were seen to be older, with significant smoking exposure and belonging to Stage 1 COPD. Conclusion: In conclusion, we demonstrated that elevated RDW levels in patients with COPD were associated with disease severity.It might be an indicator of hypoxemia. Therefore, an inexpensive and simple laboratory parameter, such as RDW, could be considered as a biomarker in the evaluation of the severity of COPD

Introduction: The first case of covid19 in India on January 31,2020.India has presently achieved over 90% recovery.9.5 million cases recovered out of 10 million reported as of December 19,2020.However,as the cohort of survivors expands, it is now being realized that a parallel epidemic of the post-COVID syndrome/long COVID is emerging.Aim:To identify and manage long covid more efficiently. Objective:To record follow up data of covid 19 survivors.Materials & Method: This is the prospective cohort study including 150 patients of,all confirmed hospitalized patients who were discharged during 2nd wave of COVID 19 from RRMCH, Bangalore, patients were contacted by telephone. Duration for 6 months April 21 to October 21. Results:Patients were found to have a direct correlation with days of hospitalization (p-0.0001,R0.773) presence of co morbidities(p-0.0001) and history of smoking(p-0.006) with Chalder fatigue score. Patients with vaccination were found to have proportionately lower CFS scores thereby indicating the importance of vaccination in prevention of Long Covid complications. Conclusion:This study makes it evident that of those who survived COVID-19 illness a significant proportion is likely to experience a post-COVID syndrome up to 6 months after the active illness