The aim of this study was to explore the treatment of knee osteoarthritis (KOA) with combined exercise therapy and to evaluate the curative effect through CT imaging technology based on optimized reconstruction algorithms. A total of 60 patients with osteoarthritis admitted to our hospital from September 2020 to March 2021 were randomly recruited as the research objects. Patients were rolled into the routine treatment group and exercise group (routine treatment + targeted exercise therapy) according to different treatments they received, with 30 cases in each group. Then, the CT imaging results of the two groups were compared after treatment. The positive rates of peripheral osteogenesis, joint space narrowing, cartilage lesions, and synovial lesions in the exercise group were inferior to those in the routine group, and the difference was statistically significant P < 0.05 . However, the change rate of positive indicators before and after treatment was not statistically significant P > 0.05 . The change range of digital pain score and Lysholm knee function score in the exercise group was significantly superior to that in the routine group, and the difference was statistically significant P < 0.05 . CT images with optimized reconstruction algorithms still had certain limiting factors in the evaluation of the curative effect of KOA and still needed to be improved. It was also proved that exercise therapy had good application value in the treatment of KOA through other methods.

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