Based on branch substructure method, this article deduces motion equation of an equipment-structure-soil interaction system. The equation is converted and applied to a shaking table real-time substructure experiment. The equipmentstructure system is adopted as experimental substructure loaded by the shaking table. Meanwhile, finite element model of soil is adopted as numerical substructure after modal reduction. An equipment-structure-soil interaction scale model is designed and tested using shaking table under different earthquake records. Comparison shows good agreement of results of experimental and finite element methods. This work also proves validity and accuracy of the proposed experimental method.
Equation of motion for an equipment-structure-soil (ESS) interaction system was derived using the branch substructure method. After rearrangement, this equation was applied to real-time dynamic substructuring shaking table (RTDSST) testing of the ESS system. This method adopts the equipment-structure (ES) subsystem as the experimental substructure and a modal reduced soil model as the numerical substructure: the former is tested via the shaking table, and the latter is numerically simulated, while realtime data communication occurs between the two substructures during testing. A scale model of the ESS system was designed and underwent an RTDSST test. The experimental data were found to be consistent with the numerical calculation results, which corroborates the reliability and validity of the proposed testing method. A comparison of the experimental results from different earthquake stages implies that seismic responses of the equipment and structure decreased in general due to the intervention of soil, but the soil effect weakened with earthquake intensity.
Objective. To investigate the effect of capecitabine versus 5-fluorouracil in advanced gastric cancer patients. Methods. We searched PubMed, Cochrane Library, Embase, and other databases from database establishment to June 2022, containing randomized controlled trials (RCT) on capecitabine and 5-fluorouracil in advanced gastric cancer patients. A meta-analysis was conducted to evaluate the effect of capecitabine versus 5-fluorouracil on overall response rate, neutropenia, thrombocytopenia, stomatitis, hand-foot syndrome, nausea and vomiting, alopecia, and diarrhea. Results. Eight RCTs with a total of 1998 patients with advanced gastric cancer were finally included, including 982 with capecitabine and 1016 with 5-fluorouracil. Compared with 5-fluorouracil, capecitabine use was significantly associated with an improved overall response rate in patients (RR 1.13, 95% CI 1.02–1.25, P = 0.02 ). Compared with 5-fluorouracil, treatment with capecitabine was significantly associated with decreased neutropenia events (RR 0.78, 95% CI 0.62–0.99, I2 = 86%, P = 0.04 ), and a decreased risk of stomatitis (RR 0.73, 95% CI 0.64–0.84, I2 = 40%, P < 0.0001 ) in patients with advanced gastric cancer. In terms of hand-foot syndrome, capecitabine was associated with increased hand-foot syndrome events than 5-fluorouracil (RR 2.00, 95% CI 1.21–3.31, P = 0.007 ). In terms of thrombocytopenia, nausea and vomiting, alopecia, and diarrhea, the effect of capecitabine and 5-fluorouracil were similar ( P > 0.05 ). Conclusions. Compared with 5-fluorouracil, capecitabine treatment improves the overall response rate and reduces the risk of neutropenia and stomatitis in advanced gastric cancer patients. It should be noted that capecitabine treatment may also increase the occurrence of hand-foot syndrome. Capecitabine is similar to 5-fluorouracil in causing thrombocytopenia, nausea and vomiting, alopecia, and diarrhea.
We demonstrate a simplified full-duplex wavelength interleaved (WI)-DWDM hybrid access radio-over-fiber (ROF) system for providing 2 GB/s wired and 1 GB/s wireless downlink and 1 GB/s uplink data data simultaneously. In this scheme, we use only one arrayed waveguide grating device to realize both the demultiplexing and multiplexing functions. Because of using only the subcarriers of the single channel to carry both the wired and wireless data, we do not need extra optical components such as interleaver to separate them at the base stations. The experimental results demonstrate that this scheme is feasible and has good transmission performance for the future WI-DWDM hybrid access ROF system. Keywords-radio-over-fiber (ROF); arrayed waveguide grating (AWG); wavelength interleaving (WI); full-duplex.I.
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