No abstract

The title compounds 10 and 11 were prepared by a one‐step procedure from 1,4‐benzoquinone (4) and pyridine‐2,4,6‐triamine (5) via an extension of the Nenitzescu reaction

Fused pyridine derivatives R 0450 Unexpected Formation of Pyridodiindole Derivatives with Cytotoxic Activity via Double Nenitzescu Reaction. -The reaction of triamine (II) with 2 equivalents of 1,4-benzoquinone (III) leads unexpectedly to a mixture of 1:1-adduct (IV) and 1:2-adducts (V)/(VI) [some yields not given]. Derivatives (V) and (VI) demonstrate cytotoxic activity against several human cancer cell lines. -(WILLEMANN, C.; WAIBEL, R.; GRUENERT, R.; BEDNARSKI, P.; TROSCHUETZ*, R.; J. Heterocycl. Chem. 45