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Introduction Prostate Cancer is the most common cancer among Nigeria men (ikueworo et al, 2013).  Prostate biopsy is the single most important procedure for establishment of diagnosis.With increasing incidence and morbidity among men of black ancestry, (Delong champs etal 2007), prostate biopsy rate, therefore, has been on the increase.Prostate biopsy involves obtaining prostate specimens for histo-pathological examinations.Various investigations and prophylactic drugs are instituted to improve the safety of the procedure. Despite all these precautionary measures, complications do occur most often self-limiting, but a few may be serious enough to warrant hospitalization.Such complications include: hemorrhage, perianal pains, heamatospemia, acute urinary retention, lower urinary tract symptoms, synocopal attacks and even death.The aim of this study is to analyze and highlight the major complications that may occur so that extra precautionary measures could be put in place while doing a prostate biopsy. Aim and ObjectiveThe study is aimed at analyzing the pattern of complications following prostate biopsies in Abia State University Teaching Hospital.