An advanced guidance law is developed against very high-speed targets. Preliminary studies have shown that the aspect angle of the interceptor at lock-on near 180 deg is a fundamental requirement for achieving small miss distance against a very high-speed target. To meet this requirement, a fuzzy guidance law in midcourse phase that is more similar to human decision making is designed. In terminal phase, a proportional and derivative-type fuzzy terminal guidance law is explored. It is shown that the integrated guidance scheme offers a near head-on homing condition before the missile enters terminal phase and provides better nal results (smaller miss distance and wider defensible volume) than the conventional guidance law. A complete simulation study is performed to show the effects of the proposed design.