Static security assessment (SSA) is an important procedure to ensure the static security of the power system. Researches recently show that cyber-attacks might be a critical hazard to the secure and economic operations of the power system. In this paper, the influences of false data injection attack (FDIA) on the power system SSA are studied. FDIA is a major kind of cyber-attacks that can inject malicious data into meters, cause false state estimation results, and evade being detected by bad data detection. It is firstly shown that the SSA results could be manipulated by launching a successful FDIA, which can lead to incorrect or unnecessary corrective actions. Then, two kinds of targeted scenarios are proposed, i.e., fake secure signal attack and fake insecure signal attack. The former attack will deceive the system operator to believe that the system operates in a secure condition when it is actually not. The latter attack will deceive the system operator to make corrective actions, such as generator rescheduling, load shedding, etc. when it is unnecessary and costly. The implementation of the proposed analysis is validated with the IEEE-39 benchmark system.

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Although it has been 30 yr since the development of derivation methods for mouse embryonic stem (ES) cells, the biology of derivation of ES cells is poorly understood and the efficiency varies dramatically between cell lines. Recently, the Rho kinase inhibitor Y-27632 and the cell dissociation reagent Accutase were reported to significantly inhibit apoptosis of human ES cells during passaging. Therefore, in the current study, C57BL/6×129/Sv mouse blastocysts were used to evaluate the effect of the combination of the two reagents instead of using the conventional 129 line in mouse ES cell derivation. The data presented in this study suggests that the combination of Y-27632 and Accutase significantly increases the efficiency of mouse ES cell derivation; furthermore, no negative side effects were observed with Y-27632 and Accutase treatment. The newly established ES cell lines retain stable karyotype, surface markers expression, formed teratomas, and contributed to viable chimeras and germline transmission by tetraploid complementation assay. In addition, Y-27632 improved embryoid body formation of ES cells. During ES cell microinjection, Y-27632 prevented the formation of dissociation-induced cell blebs and facilitates the selection and the capture of intact cells. The methods presented in this study clearly demonstrate that inhibition of Rho kinase with Y-27632 and Accutase dissociation improve the derivation efficiently and reproducibility of mouse ES cell generation which is essential for reducing variability in the results obtained from different cell lines.

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