Chronic liver injury (CLI) is a complex pathological process typically characterized by progressive destruction and regeneration of liver parenchymal cells due to diverse risk factors such as alcohol abuse, drug toxicity, viral infection, and genetic metabolic disorders. When the damage to hepatocytes is mild, the liver can regenerate itself and restore to the normal state; when the damage is irreparable, hepatocytes would undergo senescence or various forms of death including apoptosis, necrosis and necroptosis. These pathological changes not only promote the progression of the existing hepatopathies via various underlying mechanisms but are closely associated with hepatocarcinogenesis. In this review, we discuss the pathological changes that hepatocytes undergo during CLI, and their roles and mechanisms in the progression of hepatopathies and hepatocarcinogenesis. We also give a brief introduction about some animal models currently used for the research of CLI and progress in the research of CLI.

No abstract

Noise FM jamming which has wide jamming band and large noise power is widely used in processing backup jamming to radar, fuze and communication. The paper adopt DDS combines with characteristic of FPGA chip to generate noise FM jamming. The method has large improvement in precision, structure and speed, and has broad application and prospect.

No abstract

Abstract. The principles on jamming the recording device using the mobile communication GSM signals are analyzed. An idea is proposed to interfere the recording device through microwave radiation. The operating principles and defects of the recording device are discussed. The curve describing the variation in sound level readings with radiation parameters is quantitatively measured. Experiments are performed using the designed prototype. Results demonstrate the ability of the prototype to effectively suppress the normally recorded waveform.