This study aims to determine the effect of entrepreneurship training, family support, achievement motivation and self-efficacy on students' interest in entrepreneurship. This research was conducted using a quantitative approach. The research population is students majoring in Educational Administration, FIP UM, with a sample of 203 students. Data analysis using SEM with the help of the AMOS 24.0 program. The results of this study are, (1) entrepreneurship training and family support have a partial and simultaneous effect on student achievement motivation, (2) entrepreneurship training and family support have a partial and simultaneous influence on student self-efficacy, (3) entrepreneurial training , family environment support, achievement motivation and self efficacy have partial and simultaneous influence on student entrepreneurship interest, and (4) entrepreneurship training and family environment support have indirect influence on entrepreneurship interest through student achievement motivation and self efficacy.