No abstract

Background and AimsEndoscopic intervention has emerged as a first-line option for management of symptomatic pancreatic necrosis, yet endoscopic debridement limited by the lack of dedicated endoscopic tools intended for this purpose. The objectives of this study were to design and build a prototype necrosectomy device compatible for use with a flexible endoscope and capable of selective tissue fragmentation, and to test the prototype in benchtop and porcine models. Methods

expansion of the space followed by electrosurgical dissection of submucosal fibers. Once the muscle is fully exposed, the cricopharyngeus and a small amount of distal muscle is transected. The entry site into the submucosa is then closed using endoscopically deployed clips. Clinical implications: For patients with refractory cricopharyngeal bar who have limited treatment options, c-POEM allows reliable muscular division and may represent a safe and effective solution for this potentially debilitating and challenging condition.