Objective: To analyze the prevalence of electronic cigarette (e-cigarette) awareness and experimentation among university students, as well as the characteristics associated with that awareness. Methods: This was a cross-sectional study, conducted in 2015, in which 489 university students at the Federal University of Mato Grosso (Cuiabá campus), Brazil, were interviewed with the use of a specific questionnaire. We estimated the prevalence of e-cigarette awareness and use, as well as analyzing the major characteristics associated with that awareness and use. Results: The prevalence of e-cigarette awareness was 37%, and the rate of e-cigarette experimentation was 2.7%. Awareness of e-cigarettes was found to be associated with marital status, work status, the level of parental education, and the presence or absence of smokers in the family. Conclusions: A high proportion of university students were aware of e-cigarettes. Although the prevalence of those who had experimented with e-cigarettes was low, there is concern that there could be an increase in the use of these types of device. There is a need for measures targeting university students, in order to build awareness of and prevent e-cigarette use.

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RESUMOObjetivo: analisar quais os principais biomarcadores empregados no diagnóstico da sepse neonatal descritos na literatura. Métodos: foram consultadas as bases de dados dos sistemas eletrônicos Cochrane Library, PUBMED e SciELO por meio dos seguintes descritores combinados: [Neonatal OR Infants OR Newborns AND Sepsis AND Molecular Markers]. Foram incluídos artigos randomizados publicados entre 1990 a 2014 que tratavam de "marcadores infecciosos e/ou inflamatórios envolvidos na sepse neonatal" e dispunham de versão integral disponível gratuitamente no Portal de Periódicos CAPES. Resultados: do total de 655 artigos, 283 foram incluídos, sendo 47% sobre inflamação, 37% abordando inflamação/infecção e 16% infecção. Destes, 184 estavam disponíveis. Dos marcadores encontrados, os mais citados foram: PCR, PCT, IL-6, IL-10, IL-8, TNF-α, CD64, E-selectin, IL-1β, nGAL, TBARS e SAA. Conclusão: o diagnóstico por meio de biomoléculas pode ser influenciado de acordo com as particularidades das amostras, dos indivíduos estudados, características das comorbidades e pelas metodologias empregadas. A utilização conjunta dos marcadores moleculares parece ser uma tendência, cada vez mais, empregada na sepse neonatal. Por isso, esta revisão poderá contribuir em investigações futuras, uma vez que, descreve os marcadores que têm sido relatados para o diagnóstico de SIRS e sepse neonatal. Palavras-Chave: biomarcadores, sepse neonatal, recém-nascidos, neonatosABSTRACT Objective: to analyze the most used biomarkers in the diagnosis of neonatal sepsis described in literature. Methods: we searched electronic databases of Cochrane Library, PubMed and SciELO, with the following combined descriptors: [Neonatal OR Newborn OR Infants AND Sepsis AND Molecular Markers]. Randomized articles, from 1990 to 2014 dealing with "infectious and/or inflammatory biomarkers involved in neonatal sepsis" which had full version available for free were included. Results: from a total of 655 studies, 283 were included, 47% of inflammation, 37% of inflammation/ infection, and 16% of infection. From those, 184 were available, and most cited markers were: PCR, PCT, IL-6, IL-10, IL-8, TNF-α, CD64, E-selectin, IL-1β, nGAL, TBARS and SAA.