Abstract.A brief account of the geography and floristic regions of Panamá is complemented with an historical account of the liverwort studies of this country. This is followed by an annotated checklist of 289 taxa, including 93 new for Panamá. Among these are four hornwort taxa that represent the first anthocerotes reported. Each checklist entry comprises proper taxon citation, collection data and/or bibliographic references.Resumen. Una revisión de la geografía y regiones florísticas de Panamá es complementada con una nota histórica de los estudios sobre hepáticas de este país. Esto es seguido por una lista anotada de 289 taxa, incluyendo 93 que son nuevos para Panamá. Entre éstos se encuentran cuatro antocerotes que representan las primeras comunicaciones en esta División. Cada taxon ingresado contiene la citación apropiada, datos de colecta y/o referencias bibliográficas.
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