This paper develops a novel and convenient approach to deposit poly(3,4ethylenedioxythiophene)-reduced graphene oxide (PEDOT-rGO) hybrid film in aqueous solution through electrochemical process. The PEDOT-rGO film exhibited supperior charge transfer capability with charge transfer resistance of 1333 Ω.cm −2 and standard transfer rate constant of 0.145 s −1 , which makes it a promising material for electrochemical sensing applications. The glassy carbon electrode modified with PEDOT-rGO showed good electrocatalytic performance towards acetaminophen with limit detection of 5.74 μM, linear concentrations ranging from 10 to 60 μM and sensitivity of 23.5 μA.μM −1 .cm −2 . The use of acetaminophen sensor based on PEDOT-rGO in analysing Vietnamese traditional medicaments was demonstrated.
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