In the present study, we aimed to define and report the universe of ingredients used in consumer cleaning products in the United States. To develop exposure estimates associated with the use of these cleaning product ingredients, an inventory was developed using data provided publicly by product formulators. The inventory included compilation of product uses, ingredient names, and ingredient uses for over 13,000 ingredient listings from over 1,000 products surveyed. Ingredient listings were consolidated to produce the Ingredient Inventory, a list of 588 unique name-CAS registry number combinations. Ingredients were associated with specific product uses. For each ingredient in the inventory, chemical class and function were researched. Ingredient functions were defined in terms of functional-use classes (FCs). Existing FC lists provided by EPA’s Safer Choice Program, EU REACH, INCI Dictionary, manufacturer Web sites and other sources were reviewed and FCs from each source compiled and compared. FC naming conventions and assignments were then harmonized with the recently developed OECD Functional Use Category listings. This study presents the methods used to create the inventory, determine the appropriate FC(s) for each ingredient and fill data gaps using alternate sources and read-across. It further presents trends in ingredient occurrence across both FCs and broad cleaning product types, i.e. laundry care, dish care, hard surface cleaners, as well as the distribution of FC types within product types. This unique inventory of cleaning product ingredients () is hosted by the American Cleaning Institute, an industry trade association that represents the formulators of more than 90% of the consumer cleaning products in the United States. Such publicly available data can now be used for future hazard assessments, and when coupled with associated exposure assessments, employed to support screening-level risk assessment of ingredients in cleaning products as a baseline to better quantify the sustainability of consumer cleaning products in the United States.