This article presents an observational randomized prospective study done on 65 patients, who underwent major surgical interventions in the field of orthopedic surgery-total hip replacement or general surgery � total colectomy. The level of albuminemia in these cases were determined before the surgical intervention, after 6 hours of the intervention and after 24 h of the intervention. The measurements of the plasmatic concentration of the pro-inflammatory cytokines Tumor Necrosis factor -alpha (TNF-alpha) and interleukin 6 (IL6) were simultaneously done with the determination of the plasmatic levels of albumin. Values of hemoglobin and hematocrit were determined 24 h after the surgical procedure in order to exclude hemodilution, which could lead to a possible drop in the levels of plasmatic albumin. After the collection of the data, the statistical work was done and it consisted of descriptive statistics, correlation and comparison tests as well as statistical validation tests. Obtained results indicate that IL-6 plays a major role comparatively with that of TNF-alfa, regarding the decrease of the plasmatic level of albumin, and due to this, the primordial cause for hypoalbuminemia is an acute hepatic phase reaction. Supplemental permeability of the capillary wall under the action of TNF alpha has a secondary role, but could lead to a faster decrease in plasmatic albumin in the first hours after the surgical procedure.

Hypoalbuminemia occurs in about 90% of critically ill patients admitted in the intensive care unit (ICU), this is caused by an increase in microvascular permeability (capillary and venous wall) as a result of systemic inflammatory reaction (SIRS) and decreased synthesis of hepatic albumin in acute liver response. The aim of this study is to determine the incidence of hypoalbuminaemia in patients with non-septic SIRS (induced by surgical trauma or multiple trauma) and to assess the plasma albumin level as a potential biomarker of severity in the prognosis of these patients. The albumin plasma level of ICU admitted patients were determined every 24h and 48h, patients were continuously monitored for complications. Hypoalbuminemia is probably the cause of prolonged ileus, gastroparesis, sepsis, fistula and acute renal failure). The statistical processing of data consisted in compiling descriptive statistics on values of albumin, highlighting the albuminage relationship by the regression method. Calculation of mean plasma albumin values for groups of patients without clinical complications, those with clinical complications or with complications and who died and performing the Scheffe( multiple comparison test), correlation tests between albumin value at 48h and APACHE II score (prediction score Of the critical patient) as well as a descriptive analysis taking into account the 3 g / dl albumin value (factor that differentiates mild to moderate hypoalbuminemia in clinical practice) and performing the non-parametric Chi-Square test for validation of statistical analysis.

Intervention and rescue activities require knowledge of the real situation in the affected area as accurately as possible. Therefore, the physical exploration of this area is at the same time necessary and risky. The use of drones from a safe distance can protect the intervention team from exposure to unknown hazards. Endowment of the drone with a suite of sensors such as high resolution cameras, thermal imaging, infrared, and gas detection equipment permits vital data to be transmitted to the base of intervention. Hazardous areas can be studied from different angles, from an altitude that provides a panoramic view, and make available rescuers information about dangers encountered, state of access routes, number of people caught by the event, and control or protective measures that need to be taken. The current paper presents the methods for use and control of drones in support of rescue actions, resulting from tests performed by the research team, trained and certified to use drones, within the National Institute for Research and Development in Mine Safety and Protection to Explosion-NIRD INSEMEX. It was demonstrated that a drone which carries a multigas detector and a high definition video camera can help rescuers which intervene in an area with fire/toxic/flammable hazard. For such a mission, a drone must be capable to flight a long time, to carry the multigas detector and to flight secure without visual contact and without autonomous flight support in case of GPS signal lack. Flights in such conditions impose high power engines with 6-8 propellers for fine adjustments.

HighlightsLong time hospital stay and cost are reduced by parental home care, while adequate hydration maintenance scheme is sine qua non.Inadequate monitoring system and lack of funding are two important factors that can influence morbidity and mortality.The immune deficient short bowel syndrome patient is always exposed to opportunistic life threatening infections.The lack of sufficient mucosal surface and long time intestinal adaptation process is crucial in determining bowel functional capacity.Intestinal stoma compared to primary anastomosis is debatable in short bowel syndrome surgery.

The acute hepatic phase response is defined as a reaction that includes hepatic synthesis of proteins, consisting in the increase of some proteins called positive acute phase proteins and the simultaneous decrease of others called negative acute phase proteins. This study describes this hepatic reaction, based on a series of consecutive determinations, at three different time intervals (right before a major surgery event, 24 and 48 hours after the intervention), of the plasmatic levels of transferrin, albumin, fibrinogen and C reactive protein (CRP). Subsequently, the data was analyzed using Jamovi 2019, version 0.9. The inferential statistics consisted in calculating an ANOVA test that compared the values at 24 hours and 48 hours versus the values right before the major surgery. The results were validated by calculating the p value (p[0.05) as well as conducting correlation tests by determining the Pearson coefficient which shows the values of CRP, fibrinogen, transferrin and albumin are independent of each other and do not interact. The multiple ANOVA comparative test reveals the lack of interaction between the values of determined proteins, regardless of the moment of determination.