Abstract. This paper presents a complete decision procedure for the entire quantifierfree fragment of Separation Logic (SL) interpreted over heaplets with data elements ranging over a parametric multi-sorted (possibly infinite) domain. The algorithm uses a combination of theories and is used as a specialized solver inside a DPLL(T ) architecture. A prototype was implemented within the CVC4 SMT solver. Preliminary evaluation suggests the possibility of using this procedure as a building block of a more elaborate theorem prover for SL with inductive predicates, or as back-end of a bounded model checker for programs with low-level pointer and data manipulations.

Urosepsis is a very serious condition with a high mortality rate. The immune response is in the center of pathophysiology. The therapeutic management of these patients includes surgical treatment of the source of infection, antibiotic therapy and life support. The management of this pathology is multidisciplinary and requires good collaboration between the urology, intensive care, imaging and laboratory medicine departments. An imbalance of pro and anti-inflammatory cytokines produced during sepsis plays an important role in pathogenesis. The study of cytokines in sepsis has important implications for understanding pathophysiology and for development of other therapeutic solutions. If not treated adequately, urosepsis may lead to serious septic complications and organ sequelae, even to a lethal outcome.