A Computable Mine Safety Supervision (CMSS) model is constructed based on agent-based modeling and simulation (ABMS) technology and the conservation of resources (COR). This model aims to solve the mining safety problems involved with illegal mining operations and burnout among mining supervisors, in China. The model includes several types of agents: supervision agents, decision support agents, functional coordination agents, and miner agents, and it uses the Netlogo simulation platform to simulate the influence of reward and punishment on agent behavior. The simulation determines the decision support degree to gauge the influence of functional coordination and miner behavior on the burnout rate of supervision agents. We analyze the macroscopic emergence law of the simulation results. The results show the following: (1) Job Situation Adaptability (JSA) ∈ [−6.02, 2.64] ∪ [16.9, 21.93], which uses a reward strategy to guide miners to choose safe behavior and (2) JSA ∈ [2.64, 16.9], which uses a punishment strategy to restrict unsafe behavior. The decision support coefficient Sc has the greatest influence on the supervision agent’s job burnout. The functional coordination coefficient Fc has the second highest influence on job burnout and the processing effectiveness coefficient Ec has the least influence. According to the simulation results, suggestions for improving the mine safety supervision system are put forward and an improved safety management decision-making basis for reducing mine accidents is provided.