Prestasi belajar merupakan tingkat kemanusiaan yang dimiliki siswa dalam menerima, menolak, dan menilai informasi yang diperoleh dalam proses belajar mengajar. Tujuan penelitian ini untuk mengetahui pengaruh motivasi dan dukungan keluarga terhadap prestasi belajar mahasiswa tingkat II Prodi D-III Kebidanan Universitas Ubudiyah Indonesia. Jenis penelitian ini bersifat analitik dengan pendekatan cross sectional. Teknik pengambilan sampel total sampling sebanyak 73 orang. Instrumen penelitian menggunakan kuesioner dan transkrip nilai. Hasil penelitian analisis ini menunjukkan bahwa ada pengaruh motivasi terhadap prestasi belajar mahasiswa dengan nilai P-Value = 0,000 (P < 0,05) dan ada pengaruh dukungan keluarga terhadap prestasi belajar mahasiswa dengan nilai P-Value = 0,000 (P < 0,05). Berdasarkan hasil penelitian dapat disimpulkan bahwa ada pengaruh yang signifikan antara motivasi dan dukungan keluarga terhadap prestasi belajar mahasiswa.
Background Endometriois represents a gynecological disease that still becomes an issue in community. Phaleria macrocarpa is a plant native to Indonesia that contains an antioxidant substance, which may serve as apoptotic modulator and useful for angiogenesis. Objective This study aims to evaluate the effects of flavonoid isolates from P. macrocarpa (PM) on the development of granulomas, apoptosis, proliferation, and angiogenesis of the disease. Material and methods Total thirty mice ( Mus musculus ) were categorized into six groups, including the normal group (without any treatment), EMT (endometriosis) group, and EMT group treated with PM flavonoid isolates. Identification of the active compounds of P. macrocarpa was done using LC-HRMS. Measurement of granuloma scores and vascular density was done histologically. Apoptosis and proliferation analysis was performed by immunohistochemical techniques. Results There was an increase in granulomas, proliferation, and apoptosis in the peritoneal tissues of the endometriosis model. This change can be normalized by extract of P. macrocarpa . Conclusion We concluded that the flavonoid isolates from P. macrocarpa can suppress the growth of endometriosis lesions through normalization of proliferation and apoptosis. Thus, the P. macrocarpa flavonoid can be used as an alternative to inhibit the development of endometriosis.
Introduction:Endometriosis is still a problem for women all over the world. There are no studies that apply herbs, especially Scurrula atropurpurea to inhibit the development of inflammation in endometriosis.Aim:The purpose of this study was to analyze the docking of active ingredient of Scurrula atropurpurea on NFkB-IkB complex with IKK in silico way.Material and methods:The nine active ingredients of Scurrula atropurpurea analyzed here were including aviculin (CID 10391477), caffeine (CID 2519), catechin (CID: 9064), epicatechin (CID: 72276), kaempferol (CID 5280863), quercetin (CID 5280343), quercitrin (CID 5280459)), rutin (CID 5280805), and theobromine (CID 5429). The sequence of study procedures included searching for amino acid sequences and active plant component structures, protein 3D structure modeling, docking and analysis of protein-ligand interaction.Results:Regarding the NFkB-IkB complex, it was found that all active ingredients can interact where the strongest interaction sequence was rutin (-314.35 kJ/mol). Regarding the interaction between IKK and NFkB-IkB, the nine active ingredients can reduce bond energy, except rutin.Conclusions:the active ingredients of Scurrula atropurpurea having the potential effect as anti-inflammatory is rutin so that it can be isolated and used as an alternative ingredient in inhibiting inflammation in endometriosis.
Sectio Caesarea is surgery to give a birth of a fetus through the abdominal wall. This surgery has an impact on the pain that is caused by the incision. Pain management ncluding the usagenon-pharmacological and pharmacological approaches. Onenon-pharmacological approaches are breathing in relaxation techniques and foot-hand massage techniques. The purpose of this study was to look at the effectiveness of breathing relaxation and foot and hand massage techniques for postpartum caesarean delivery in Langsa Hospital in 2018. The designs used in this study were quasi-experimental, pre-test and post-test designs Tests used in bivariate analysis with statistical tests Paired sample t-test and t-test Independent. The results of the Statistical Test using the Independent T-test obtained an effective Foot And Hand Massage technique for reducing pain intensity with a P value of 0,000. Foot and hand massage techniques can promote blood circulation, reduce pain, reduce the number of drugs and side effects. Hand and foot massage techniques are cheaper, low risk, and easy to apply. AbstrakSectio Caesarea (SC) merupakan tindakan pembedahan sebagai upaya lahirnya janin melalui dinding abdomen. Tindakan pembedahan berdampak terhadap munculnya rasa nyeri akibat irisan. Penatalaksanaan nyeri diantaranya menggunakan pendekatan farmakologis dan non farmakologis. Salah satu pendekatan non farmakologis adalah teknik relaksasi nafas dan foot and hand massage. Tujuan penelitian ini adalah melihat efektifitas teknik relaksasi pernapasan dan foot and hand massage pada ibu pasca salin section caesarea di RSUD Langsa Tahun 2018. Desain yang digunakan dalam penelitian ini adalah Quasi eksperimen, pre-test and post-test desain. Uji yang digunakan pada analisis bivariat dengan uji statistic Paired sample t-test dan uji T-Independent. Hasil penelitian menunjukan bahwa hasil Uji Statistik mengunakan Uji Independen T-test didapatkan teknik foot and hand massage efektif untuk pengurangan intensitas nyeri dengan nilai P value 0,000. Teknik pijat kaki dan tangan dapat meningkatkan sirkulasi darah, mengurangi rasa sakit, mengurangi jumlah obat dan efek samping. Teknik foot and hand massage lebih murah, berisiko rendah, dan mudah diterapkan.
The implementation of Clean and Healthy Lifestyle in the midst of the COVID-19 pandemic has become a serious problem in society. The application of clean and healthy living behavior in everyday life in the household can reduce the risk of disease and nutritional status in children. Achievement of optimal nutritional status can be influenced by several factors, namely direct, indirect and root causes. Direct factors consist of food consumption and infection status. Indirect factors consist of availability, food consumption patterns, hygiene, sanitation, and environmental health. The purpose of this study was to determine the Clean and Healthy Lifestyle with Child Nutritional Status in the midst of the Covid-19 Pandemic. This study is a systematic review using online databases, namely Scholar, Sciencedirect, ProQuest, and EBSCO. The keywords used are clean and healthy living behavior, Child Nutrition Status, Covid-19 Pandemic.The selection process used the PRISMA protocol so that 15 articles were obtained that met the inclusion criteria. The findings of the review show that adopting a good, clean and healthy lifestyle affects children's nutritional status. The application of clean and healthy living habits in household arrangements is influenced by knowledge, culture, socioeconomics, beliefs, and the availability of facilities or technologies. During the Covid-19 pandemic, parents can play a role in reminding, educating, providing role models and support, advising, and emphasizing the importance of clean and healthy living.
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