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K E Y W O R D S : aluminium salts, eosinophilic cellulitis, patch test, vaccine reaction, Wells cellulitis, Wells syndrome CASE REPORT Case 1. A 10-year-old boy with a past history of atopic dermatitis and allergic rhinitis presented with pruriginous erythematous annular plaques with vesicles on the dorsum of his right foot ( Figure 1A). The eruption appeared 12 days after he had received hepatitis B and human papillomavirus vaccines (Recombivax HB, Cervarix). Laboratory tests revealed eosinophilia of 1.000 × 10 9 /L (normal range < 0.600 × 10 9 /L). Cutaneous biopsy showed dermal and subcutaneous lympho-eosinophilic infiltrate with rare flame figures ( Figure 1B), suggesting the diagnosis of Wells syndrome. He was successfully treated with prednisone 0.5 mg/kg daily tapered over 6 weeks.Case 2. A 12-year-old girl with a past history of atopic dermatitis presented with pruriginous violaceous annular plaques on both legs (Figure 2A). The eruption appeared 14 days after she had received her second injection of human papillomavirus vaccine (Gardasil 9). Interestingly, 2 weeks after receiving her first injection, she had developed the same cutaneous eruption that persisted for 2 months, but she did not seek medical care at that time. No laboratory tests were done. A cutaneous biopsy showed an interstitial dermal infiltrate composed of lymphocytes, histiocytes, and eosinophils with numerous flame figures ( Figure 2B), also consistent with a diagnosis of Wells cellulitis. She also was successfully treated with prednisolone 0.5 mg/kg daily tapered over 2 weeks.

With the COVID-19 pandemic, vaccines have been administered all around the world probably more than ever. Even though they are considered safe, with such a huge quantity of doses used, many adverse effects including cutaneous ones were reported. We report here the case of a male adult with a history of monoclonal gammopathy of undetermined significance who presented with an extensive cutaneous eruption of indurated erythematous papules and plaques 2 days after receiving his first dose of Moderna COVID-19 vaccine (mRNA-1273 SARS-CoV-2 vaccine). Histopathology was compatible with a histiocytoid Sweet syndrome and history suggested that the vaccine contributed to the eruption.

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Sarcoidosis is an inflammatory multisystemic disease of unknown etiology with multiple presentations of cutaneous lesions. It characteristically infiltrates scars due to several kind of trauma such as surgery, tattoo and even herpes zoster. We present a case of a 65-year-old woman with progressive distal paresthesia and motor weakness. She was referred to our dermatology clinic for a new violaceous nodular plaque within an old melanoma scar on the posterior neck. On positron emission tomography–computed tomography, there were multiple enlarged thoracic lymphadenopathy and a fluorodeoxyglucose-avid cutaneous lesion on the posterior neck, right in the melanoma scar. Cutaneous and nerve biopsies showed non-necrotising granulomas, supporting the diagnosis of systemic sarcoidosis and excluding melanoma recurrence with metastasis. It is the first case of cutaneous sarcoidosis arising within a melanoma scar. Interestingly, patients with melanoma have a higher risk of sarcoidosis.