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The development in the industries has necessitated the growth of transportation methods. Due to the variation in the transportation systems, many problems seem to arise in the present times. One such problem is the stochastic fuzzy transportation problem (SFTP). The SFTP is a chance-constrained programming (CCP) problem with probabilistic constraints where supply and demand are randomness, and the objective function is in fuzzy nature. In this paper, we have developed three models for the SFTP, where the constraints are mixed type following Weibull distribution (WD). The aim of the research work is to optimize the transportation cost in FTP under probabilistic mixed constraints. In order to achieve this, the cost coefficient of the fuzzy objective function is converted to alpha cut representation, and the probabilistic mixed constraints are converted to deterministic form by using the WD. The proposed models are illustrated by providing a numerical example, and the problem is solved using Lingo software. It is worth pointing out that these models are constructed from different points of view. The decision-maker’s (DM’s) preference has the final say in the usage of the models. A sensitivity analysis (SA) is performed to explore the sensitivity of the parameters in the proposed model.

Leukotrienes formed by the action of 5-1ipoxygenase on arachidonic acid are a group of endogenous compounds active in hypersensitivity reactions and inflammation. In this report the formation of LTB4 from LTA4 was measured by incubating lung microsomes from normal and exercised rats tO ~ determine whether LTB4 may have a role in the mediation of exercise-induced oxidant stress. Exhaustive exercise in the form of swimming results in the enhanced production of LTB4 in lung microsomes. Further, free radicals measured by ESR spectroscopy were also significantly increased in lung tissue from exercised rats. These results suggest a role for LTB4 in the mediation of lung tissue damage during exercise-induced oxidative stress.

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