The synthetic progestins, norethynodrel and norethindrone, given neonatally to female hamsters caused masculinization of the genitalia, increased masculine sexual behaviour in the adults, and reduced spontaneous and hormone-induced female sexual behaviour. Neonatal progesterone treatment did not masculinize female hamsters but diminished hormone-induced feminine behaviour. Dydrogesterone neither masculinized nor defeminized female hamsters.
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