An isolator constructed in fibreglass was equipped with facilities for performing dental surgery on germ-free rats and then maintaining them in the germ-free state for a period following the surgical procedure. The main unit was sterilised with peracetic acid, and the ancillary equipment by gamma radiation.

A method is described for the production of primary chick embryo cell suspensions that allows the processing of from 200 to several thousand embryos daily at a significantly lower cost than with other methods. Special apparatus enables high yields of cells, free of microbial contamination to be produced under controlled conditions with the minimum of supervision.