Sarkuland Kenkiyak settlements are located in the Aktobe province, at18-20 km from the oil and gas producing field "Zhanazhol", in the northwest region of the Republic of Kazakhstan. To evaluate the exposure of the adult male and female population living in Sarkul and Kenkiyak settlements, a single medical study was conducted. The nonparametric method of the Spearman correlation analysis was performed between the mean concentration of substances exceeding the Maximum Permissible Concentration and the classes of newly diagnosed diseases. Selection and analysis of air samples was carried out according to the developed research protocol; the qualitative-quantitative analysis was carried out on the Gas analyzer HANK-4 apparatus. Significant pollution of atmospheric air by carbon monoxide, benzapyrene, dust and phenol were identified in places. Correlation dependencies between these pollutants of air and the diseases of the population revealed as a result of medical examination are established, as a result of diseases of the circulatory system, ear and mastoid process, nervous system and digestive organs; between the concentration of carbon monoxide and diseases of the circulatory system, the digestive system, the genitourinary system and the musculoskeletal system; between nitric oxide and diseases of the digestive system and the circulatory system; between benzopyrene and diseases of the digestive system, the genitourinary system and the nervous system.

The article analyzes statistical data for the adult population of the oil and gas producing region at the Aktobe district over 2011-2015. Data on the incidence of malignant (reporting statistical forms No. 35 and No. 7) of the adult population of Mugalzhar, Temirsky district in the Aktobe region were studied in the process of the implementation of the research. In the work, there were used statistical and epidemiological methods. There was a decline in the primary incidence of malignant tumors (MT) in the adult population in Mugalzhar region (there is a gradual decrease from 2011 till 2014, in 2015 -the sharp decrease of the indices of the primary incidence) and Kobdinsky region (there is a decrease of the MT from 2013 and an increase in the rate of growth in Temirsky region (the incidence of MT decreases from 2011 till 2013, the trend of increasing primary indices is traced from 2013) during the period under review. Ranking of the MT with the first time established diagnosis among the adult population living in the Mugalzhar district showed the women’s breast cancer to held the first place, the second - the esophagus, the third place is the uterus. The elderly population of the Temir district is ranked first with MT of the esophagus, on the second - MT of tracheaetracheae, bronchus, lung, in third place - MT of the women’s breast. Among the adult population of the Kobda district, which is the control, the MT of the stomach is leading, after it the MT of tracheae, bronchus, lung, the MT esophagus is on the third place. The statistically significant direct, strong correlations between the annual average daily concentration of carbon monoxide, nitric oxide, hydrocarbon in the atmospheric air and the index of the MT incidence (body of uterus, uterine cervix, breast, mammary gland) at the adult population was revealed. In the Mugalzharsky and Kobdinsky districts the proportion of people living by 2015 more than 5 years from the date of diagnosis is higher than in the Temir district. In the Temir district, the detection rate among newly registered MT patients, in comparison with the Mugalzhar and Kobdinsky regions is high at the I-II stages, and at the IV stage.

The article analyzes statistical data for the adult population of the oil and gas producing region at the Aktobe district over 2011-2015. Data on the incidence of malignant (reporting statistical forms No. 35 and No. 7) of the adult population of Mugalzhar, Temirsky district in the Aktobe region were studied in the process of the implementation of the research. In the work, there were used statistical and epidemiological methods. There was a decline in the primary incidence of malignant tumors (MT) in the adult population in Mugalzhar region (there is a gradual decrease from 2011 till 2014, in 2015 -the sharp decrease of the indices of the primary incidence) and Kobdinsky region (there is a decrease of the MT from 2013 and an increase in the rate of growth in Temirsky region (the incidence of MT decreases from 2011 till 2013, the trend of increasing primary indices is traced from 2013) during the period under review. Ranking of the MT with the first time established diagnosis among the adult population living in the Mugalzhar district showed the women’s breast cancer to held the first place, the second - the esophagus, the third place is the uterus. The elderly population of the Temir district is ranked first with MT of the esophagus, on the second - MT of tracheaetracheae, bronchus, lung, in third place - MT of the women’s breast. Among the adult population of the Kobda district, which is the control, the MT of the stomach is leading, after it the MT of tracheae, bronchus, lung, the MT esophagus is on the third place. The statistically significant direct, strong correlations between the annual average daily concentration of carbon monoxide, nitric oxide, hydrocarbon in the atmospheric air and the index of the MT incidence (body of uterus, uterine cervix, breast, mammary gland) at the adult population was revealed. In the Mugalzharsky and Kobdinsky districts the proportion of people living by 2015 more than 5 years from the date of diagnosis is higher than in the Temir district. In the Temir district, the detection rate among newly registered MT patients, in comparison with the Mugalzhar and Kobdinsky regions is high at the I-II stages, and at the IV stage.