Current advances in the development of tools of environmental monitoring for anticholinesterase agents are considered. The aim of this analysis was to substantiate the most promising trends in the develop ment of an up to date biosensor based on cholinesterase inhibition with an optimum sensitivity-analytical signal formation time relation for the monitoring of atmospheric air for organophosphorus warfare agents and insecticides.

Abstracts-A rapid test for amanitins is proposed on the basis of their complexation with ethydium bromide leading to an intensively fluorescent adduct; the fluorescence band of the product has a shorter wavelength than that of ethydium bromide, which ensures the high specificity of the analysis. The fluorescence intensity in the system of ethydium bromide -amanitin grows linearly with the concentration of amanitin in the range 0.2-1.7 μM at the constant concentration of ethydium bromide, 0.6 μM. The detection limit is 1 μM, the time of the development of the analytical signal is up to 5 s.