With the scope of bischalcone-based copolyesters can be used as semiconductors; two copolyesters were synthesized by the solution polycondensation method. The Bischalcone diol was analyzed by UV-Visible, FTIR, NMR (1H, 13C NMR) spectroscopy. Using the UV-Visible data, the bandgap energy of the Bischalcone diol was calculated and found to be 2.82 eV. The Physico-chemical properties like Inherent viscosity and refractive index of the copolyesters were determined. Spectral studies such as FTIR, 1H and 13C NMR spectroscopy. The thermal property of the copolyesters was analyzed by differential scanning calorimetry. The melting temperature of the PTMI is observed at 320°C, and PTMT exhibits 360°C. The PTMT shows higher stability than the PTMT copolyester. The highest ionic conductivity for PTMI is 3.50 x 10-4 (S cm-1). The PTMT copolyester shows -0.0035 KJ mol-1 whereas the PTMI copolyester shows 0.0005 KJ mol-1. The electrochemical impedance analysis and conductivity measurement were examined for the two copolyesters expecting semi-conducting behavior which can be a good candidate for the optoelectronics application.

Chalcones (1,3-diaryl-2-propane-1-ones), biogenetic precursor of open chain flavonoids, which are highly multifunctional proven to have antitumor activity either in-vitro or invivo and their target cover all of the actions of tumour cells. Chalcone derivatives exhibit antitumor activity by anti-initiation, apoptosis induction, antiproliferation, antimetastasis, antiangiogenesis and so forth. We synthesized six copolyesters and were characterized by UV, FT-IR, ¹H NMR, ¹³C NMR. Their thermal stability was studied by DSC and TGA. Cytotoxicity activity of these copolyesters was evaluated by studying their responses to MDA-MB-231 Cell Line (human Breast Cancer) by MTT Assay. UV, FT-IR, ¹H NMR, ¹³C NMR confirmed the insertion of correct functional groups. DSC and TGA showed that the synthesized compounds were of good thermoregulatory we. The drug, PTSH was effective at 10 µg/mL and 51 % inhibition was observed at 100 µg/mL. Most importantly, the drug, PITI was more significant at 0.1 µg/mL concentration itself and 58 % inhibition was noted at 1 µg/mL.