Im Zusammenhang mit pharmakologischen Untersuchungen werden einige der Titelheterocyclen synthetisiert.

A number of compounds derived from the [l]benzopyrano[4,3-6]indole and 6H-[1] benzopyrano[4,3-6]quinotine systems have been prepared from chroman-4-one and its 6-chloro-and 6-methyl-derivatives, and their physicochemical and biological properties investigated ; analogous derivatives of the [I] benzothiopyrano[4,3-b]indole system were prepared from 6-chloro-and 6-methoxy-thiochroman-4-one. The majority of the compounds synthesised displayed high zoxazolamine hydroxylase inducing activity.

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2‐Amino‐dibenzo‐p‐dioxin (I) und die Bromketone (II) ergeben die Substitutionsprodukte (III), die in Gegenwart des Hydrobromids von (I) zu den Indolo‐dibenzo‐p‐dioxinen (IV) cyclisieren.