Occasional use of the probiotics Levisel SB Plus and Tsellobacterin – T in a dose 0.50 kg/t of the mixed fodder in a diet of the laying hens at the age 21-26, 34-39 и 45-48 weeks has increased metabolic processes in the body of a bird and productivity of the laying hens in a group with Levisel SB Plus by 10.6 %, with a dash Tsellobacterin – T – by 16.1 %, but it did not affect the weight of the egg during all periods of the productive cycle. The egg incubation results showed that probiotice Levisel SB Plus increased egg hatability by 4.1%, Tsellobacterin-T by 6.2%, their fertilization by 2.1 and 4.2%, the withdrawal of young chickens by 3.5% and 5.1%. The addition of probiotics did not change the hatchability of eggs (93.22 and 93.17%) in these groups, but reduced the amount of unfertilized eggs by 1.8 and 10.3%. There was a higher content of carotenoids and vitamin A in the eggs of the laying hens and in the body of daily chickens. Using the probiotics in the diet of laying hens of the parent herd has reduced the cost of feeding for 10 eggs by 8.2-8.5% , with a dash of Levisel SB Plus by 15,0-15,4%, with a dash of Tsellobacterin – T to the weight of the egg by 1,8-9,7% and 15.3-15.5% respectively. At the same time, the payment of food products increased in the group using Levisel SB Plus by 10.3-10.7%, with Tsellobacterine - T by 20.9- 21.7%, the profitability of production increased by 13.1 and 22.3%.

The use of two similar feed additives Sorbitox and Probitox in the diet of replacement stock and subsequently in the diet of laying hens, at a dose of 0.50 kg/t of feed allowed to increase the poultry survival rate at 18 weeks of age by 1.4% with the addition of Sorbitox and 6.4% - with Probitox, the group uniformity by 5.3 and 7.3%, respectively, in comparison with the control group. At the same time, the culling of birds in the experimental groups decreased due to endoenteritis and necrotic enteritidis, and the antibody titer to Gumboro disease increased in the blood. During the productive period of laying hens, the difference in the antibody titer was significantly higher, as was the livestock survival rate. The tested feed additives contributed to a better development of ovogenesis organs. As a result, the egg productivity of chickens with Sorbitox was higher than the control group by 6.5%, with Probitox – by 11.6%. The study of the egg incubation qualities showed that the young stock hatching rate from an average egg size in the group with Sorbitox was 6.9% higher than the control group, with Probitox – by 11.0%, and the hatchability of eggs was 1.1 and 1.6% higher than in the average one. In laying hens at the beginning and at the end of egg laying, the number of infertile small eggs decreased in the group with Sorbitox by 0.60%, with Probitox - by 1.0%, large eggs – by 1.23 and 2.45%, respectively. The chicken hatching rate from small and large eggs in poultry of the experimental groups exceeded the control by 2.9-5.9% at the beginning of egg laying, by 10.0-14.8% at its completion at the age of 56 weeks. The addition of Sorbitox in the diet of replacement stock allowed to reduce feed costs for growing one head of service pullet by 6.9%, with Probitox – by 12.6%, to increase the production profitability by 5.5 and 7.8%, and in laying hens of experimental groups, feed costs decreased by 4.4 and 10.0%, profitability increased by 2.0 and 5.3%, respectively.

The diet of monogastric animals should be adjusted for vitamin and mineral nutrition during the period of growing and economic use. They affect all types of metabolism, especially in the last third of gestation of sows and the development of young pigs in the postnatal period. For sows throughout the period of gestation and suckling, it is important to include in the diet such biogenic element as folic acid, as well as a set of essential trace elements (copper, zinc, cobalt, manganese) and group B vitamins, the use of which during the entire production cycle helped to improve prolificacy of sows by 15.2%, the average increase was 8.8% and the safety of young pigs dairy period of cultivation is 7.2%, which reduced the cost of feed for growing one reared pig by 10.6-18.1 %.

The development of the livestock and poultry industry in the Chelyabinsk region is increasing every year, in this regard, there is a problem of disposal of animals and poultry waste products. The development of a method for increasing the degree of biological full-value of the processing waste products of monogastric animals and birds using Hermetia illucens larvae, which will further make it possible to solve the problem of environmental pollution and obtain an alternative feed protein. Studies have been conducted to obtain a substrate using bacteria - Bacillus subtilis. The chemical composition of biohumus was determined. The composition of the biomass of Hermetia illucens larvae grown on a substrate enriched with a probiotic preparation, namely the content of crude protein and amino acids, was determined.