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IntroductionPatients who are suffering from different type of drugs have special individual and psychological problems. These changes are important for regulation and to control their behaviour.ObjectivesTo study the psychological characteristics and personal resources of the patients who are suffering from abuse of drugs.MethodsFifty patients were studied, 63.3% men and 36.7% women and in the ages of 18–21 years. Following psychodiagnostic methods are used: Kettel's sixteen personality factor test, Leonhard-Shmishek's personality test, scale of reactive and personal anxiety Spielberger-Hanin.ResultsAmount those patients were suffering from different type of drugs: synthetic cannabinoids-66.7%, 20% were dependent on synthetic cathinone and 13.3% were dependent on opiates (heroin). According to Leonhard-Shmishek's scales, the most often of personality disorders were dysthymic type, hyperthymic type and explosive type. According to Kettel's scale were indicated the leading individually-psychological properties in more than half of the subjects is the development of abstract thinking, free thinking, impulsiveness, lack of confidence to the authorities, the high emotional tension, emotional instability and irresponsibility. An analysis of global factors indicative of the severity indices of extraversion. According to Spielberger-Hanin's scale, 80% of patients with substance abuse had mild level of situational and personal anxiety, which can be identified as an important psychotherapeutic resource.ConclusionsAccording to scales, the most often of personality disorders were dysthymic type, hyperthymic type and explosive type. Eighty percent of patients with drug abuse had mild level of situational and personal anxiety. This feature is main of predictor as an important psychotherapeutic resource.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Identifying the patterns of neurocognitive disorders in pubertal schizophrenia is actual.MethodsBenton Test of visual retention, methods of forward and reverse bills, Bourdon correction sample, Wechsler's subtests (subtest 11 – “Encryption”, subtest 12 – “Labyrinths” 1, 2, 3, 4, 5), Trail Creating a Test Part A.ResultsAll patients were divided into 3 groups. The first group (schizophrenia) and second group (other psychic disorders) showed the worst results than healthy subjects. Qualitative analysis of the “Benton Test” results showed similar variations of difficulty and types of errors in the subjects of the first and second groups – ignoring the number of the figure sides, as well as difficulties in the structuring element of the image corners. The “Methods of forward and reverse bills” demonstrated the fatigue and attention instability. “Bourdon test” showed a high level of the stability index (K = 0.09). Wechsler's subtest “Encryption B” obtained poor results, indicating a pathological decrease in visual-motor speed. During the subtest “Labyrinths 1, 2, 3, 4, 5” the subjects of first and second groups exceeded the allowable time limit, but the first group of schizophrenia patients allowed more blunders during pubertal study (ignored the walls of the maze, torn pencil despite the given instructions). The test groups 1 and 2 while passing “Trail Creating a Test Part A” have shown good results – job data did not cause difficulties and carried out in accordance with the specified instructions.ConclusionsNeurocognitive disorders allow to confirm the presence of morphological and functional brain changes when endogenous mental illness occurs.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Clinical symptoms, course and outcomes of paranoid schizophrenia are polymorphic. Reliable predictors of severity and activity of schizophrenic process could provide clinicians important prognostic information for adequate and timely implementation of therapeutic and rehabilitative measures. Overall, 206 patients with paranoid schizophrenia were examined. Clinical predictors were collected from hospital records and interviews. BDNF gene Val66Met polymorphism (rs6265 G>A), DRD2 gene C939T polymorphism (rs6275C>T) and 5-HTR2A gene T102C polymorphism (rs6313 T>C) were studied as potential markers of prognosis for paranoid schizophrenia. Results of research testify that the DRD2 gene C939T polymorphism and 5-HTR2A gene T102C polymorphism cannot be used as predictors of the severity and activity of paranoid schizophrenia. The MetMet genotype of BDNF gene Val66Met polymorphism can be used as marker of favorable prognosis for paranoid schizophrenia. Schizoid, epileptoid, psychasthenic and conformal accentuation of personality in the premorbid, early onset of psychosis, paranoid and hallucinatory-paranoid variants of onset predicted more expressed severity of paranoid schizophrenia. These prognostic factors can be taken into account in clinical practice.Disclosure of interestThe authors have not supplied their declaration of competing interest.

IntroductionThe determining of the actual number of people with mental disorders and their spreading by nosology still remains actual, especially according to different regions.ObjectivesThe determining of the psychiatric services effectiveness in Saratov region on the basis of comprehensive analysis of its’ clinical, statistical and epidemiological characteristics.MethodsThe analysis of mental state indicators based on the example of adults’ schizophrenia Saratov region in dynamics for 10 years (2005–2015) in comparison with Russian Federation.ResultsOver the past 10 years the number of clinically supervised patients with schizophrenia decreased at 0.9% in the city and 2.2% in region population. This is consistent with the tendency of schizophrenia morbidity in Russian Federation over the same period. The number of supervised adult patients with primary diagnosed schizophrenia in Russia remained at the same level and amounted to 10.8 per 100 thousand population. At the same time the noticeable fluctuations in the number of this patients’ category were observed in Saratov and Saratov region. Over the past 10 years, the proportion of patients with primary diagnosed schizophrenia disability in the class structure of mental disorders is quite high, averaging of 41.1% in Saratov region. Analyzing the number of patients with re-confirmed disabilities the gradual decline from 1846 to 755 people (at 59.1%) was found.ConclusionsThe mental health analysis of Saratov region population allows to suggest the long-term forecast of mental disorders’ morbidity, to analyze the level of disability due to schizophrenia, to develop recommendations for the optimal regional model of psychiatric services.Disclosure of interestThe authors have not supplied their declaration of competing interest.