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Postpneumonectomy syndrome is a rare and delayed complication of pneumonectomy. This syndrome is caused by the shifting and rotation of the heart and mediastinum into the empty hemithorax. It can be corrected by inserting prosthesis in the empty side of the chest. We experienced a case of postpneumonectomy syndrome in 17 year-old girl that followed by right pneumonectomy for multi-drug resistance tuberculosis (MDR-TB) 9 months ago. The corrective surgery of postpneumonectomy syndrome does not seem to be familiar with anesthesiologists. We report this case with references, as we were unable to find any case report about this maneuver.