Streptozotocin (STZ) is a cytostatic antibiotic produced by Streptomyces achromogenes. It is an inhibitor of DNA replication showing a special affinity for pancreatic β-cells DNA. It is used in medicine as an antineoplastic agent (indicated in the treatment of malignant neoplasms of pancreas) and in scientific research to induce hyperglycemia, insulitis, diabetes mellitus (DM), Alzheimer's disease on experimental animals. Insulinopenia syndrome is called 'streptozotocin diabetes', caused by necrosis of the pancreatic β-cells. STZ induced DM offers a very cost-effective and expeditious technique in medical research.

Summary Objective: The aim of the study was to determine differences in the range of socio-demographic variables, selected clinical variables, temperament and character traits, coping with stress strategies and the level of aggression in alcohol addicts with or without a history of suicide attempt(s). Methods: The study involved 90 people addicted to alcohol, treated in inpatient alcohol dependence treatment program. In order to collect data on socio - demographic variables and selected clinical variables, a self-made questionnaire was used. The severity of alcohol dependence was verified using the MAST and SADD scales. Characteristics of temperament and character were examined with the TCI questionnaire. The BPAQ and COPE questionnaires were used to examine the level of aggression and styles of coping with stress. Results:Out of 90 subjects with alcohol dependence syndrom, 20% had attempted suicide in the past. The respondents with a history of suicide attempts were statistically significantly younger, were characterized by a younger age of alcohol drinking initiation and the initiation of regular alcohol drinking, and a greater severity of alcohol dependence in the MAST and SADD scales. A significantly larger percentage of respondents who had attempted suicide inflicted self-injury in the past, used other psychoactive substances as well as hypnotics and sedatives. The subjects with a suicide attempt in the interview obtained statistically significantly higher scores in terms of the level of aggression, harm avoidance and self-directedness, and more often used the style of coping with stress based on avoidance and accepting the situation. Conclusions: The obtained results correspond with data available in the literature and may provide a foundation for theoretical models explaining the phenomenon of suicidal behavior in alcohol addicts as well as for suicide prevention programs in this group of patients.

Sweet taste accompanies our lives since childhood. Sugar is commonly used in industrial production. Increased consumption of simple sugars has been observed since many years. Sugars come in different forms and one of them-glucose-fructose is on scientists aim because if it's impact on health. Fructose has unique metabolic features, that could be harmful for human organism. Excessive consumption of this substance contributes to obesity pandemic, development of diabetes mellitus and cardiovascular disease. Obesity affects in particular children and teenagers.[1] High consumption of fructose disturb sense of hunger and satiety.

Electroconvulsive therapy (ECT) is one of the most effective and safe methods of treatment used in psychiatry. The history of ECT in Poland dates back to 1861, when Vilnius doctor Klemens Maleszewski successfully applied electricity obtained from a galvanic cell to treat a patient with catatonia. The modern history of the use of electricity to induce seizures dates back to 1938, when Bini and Cerletti performed the first ECT on a patient suffering from paranoid schizophrenia. Although ECT is thought to be a very safe, well-known and effective procedure, patients are still afraid of undergoing ECT due to bad reputation of this method.

Serotonin reuptake inhibitors (SSRIs), along with serotonin norepinephrine reuptake inhibitors (SNRIs) and norepinephrine dopamine reuptake inhibitors (NDRIs), are the first-line drugs in the treatment of depression. Pharmacotherapy of psychiatric disorders with SSRIs is widely practised. Although SSRIs are thought to be relatively safe group of drugs, it is worth to remember that particular SSRIs agents are related to unique secondary and side effects. Knowledge about basic differences between each medication in this group is essential to choose suitable treatment for every patient.